Record-breaking Frank Rubio, a NASA astronaut, has finally touched down and is experiencing Earth’s gravity for the first time in almost a year. On Wednesday at 5:17 p.m. local time (7:17 a.m. ET), Rubio and his two Russian colleagues, cosmonauts Sergey Prokopyev and Dmitri Petelin, parachuted to a touchdown in Kazakhstan aboard the Russian Soyuz MS-23 spacecraft.
Rubio, who was only anticipated to stay six months on the International Space Station, came to an unexpected and lengthy conclusion with the arrival of the crew. Instead, he spent a total of 371 days in space after it was discovered that his first vehicle was leaking coolant while he was moored to the orbiting station.
For the longest period of time a US astronaut has ever spent in microgravity, Rubio’s stay set a new record. He also made history by being the first American to spend a complete year in orbit.
Rubio’s record-breaking mission also had several other significant firsts for him: this was his first trip to space after being chosen for the NASA astronaut corps in 2017, and before the start of the mission, he made history by being the first astronaut of El Salvadoran descent to go to low-Earth orbit.
In a recent interview with CNN, Rubio stated that he “probably would have declined” the job before starting training if he had realised his time on the space station would be twice as long as first anticipated.
And it’s solely due to family issues that occurred during the past year, he added. And I would have simply had to say, “Thanks, but no thanks,” if I had realised that I would have to miss those crucial events.
Rubio, a father of four, will likely start his return trip from the Soyuz spacecraft’s landing location close to the town of Dzhezkazgan in Kazakhstan. Before boarding an aircraft to Houston, he will first fly to Karaganda, which is located around 330 miles (530 km) northeast of Dzhezkazgan.
According to NASA, Rubio and his fellow crew members covered a total distance of 157.4 million miles (253.3 million km) and performed 5,963 Earth orbits.
Rubio broke NASA’s Mark Vande Hei’s previous record for the longest space stay by a US astronaut, which stood at 355 days, established in 2022. The world record for the longest stay in space is held by the late Russian cosmonaut Valeri Polyakov, who spent 437 continuous days in orbit aboard the Mir space station between January 1994 and March 1995.
US and Russian space cooperation
As part of a ride-sharing arrangement worked out between NASA and Roscosmos, the Russian space agency, in the summer of 2022 amid Russia’s invasion of Ukraine, Rubio travelled to the space station aboard a Russian spacecraft. The seat-swap plan was an effort to uphold long-standing protocols that tried to guarantee access to the space station for both the United States and Russia — the outpost’s major operators — should either nation encounter spacecraft problems that kept their personnel grounded.
On September 21, 2022, Rubio, Prokopyev, and Petelin launched aboard the Soyuz MS-22 craft and arrived at the International Space Station (ISS) three hours later in safety. They then started working inside the orbiting laboratory while the Soyuz capsule remained connected to the space station’s exterior.
Rubio expressed his gratitude to his family at a press conference last week, saying that their “resilience and strength has carried me through this entire mission.”
Less than three months into the Soyuz MS-22 crew’s journey, coolant started to leak from the craft. Roscosmos’ investigations, which were later examined by NASA, revealed that the spacecraft was probably hit by a tiny object in orbit. A micrometeorite or piece of orbital debris, a growing concern in the increasingly crowded environment of low-Earth orbit, was found to be the perpetrator. After it was determined that the Soyuz MS-22 spacecraft was unfit to return the crew, Roscosmos moved fast to launch a new vessel, the Soyuz MS-23, in February.
But Rubio and his companions were still unable to go back home: Instead, officials decided to extend their stay as Roscosmos prepared to launch yet another Soyuz spacecraft with a new crew to take their place.
Space station crew rotation
Rubio’s return on Wednesday was made possible by the Soyuz MS-24 spacecraft, which was finally prepared this month and sent NASA astronaut Loral O’Hara, Roscosmos cosmonauts Oleg Kononenko, and Nikolai Chub to the space station on September 15. Rubio, a doctor and military helicopter pilot with more than 600 hours of combat experience, recognised that due to the effects that prolonged stays in microgravity may have on the body, he probably won’t be going back to his pre-spaceflight life right away.
It’ll take two to six months before I can practically declare that I feel normal because we aren’t walking or supporting our own weight while in space, he added. He is eager to experience many earthly wonders, though: “Up here we kind of have the constant hum of machinery that’s keeping us alive,” he remarked in a space interview. I’m looking forward to spending some time outside and relaxing in the calm.
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Hier kommt das Hormon meist in Form eines Gels für die Aufnahme über die Haut
zum Einsatz. Der Testosteron-Mangel darf in dieser Weise nur dann ausgleichend behandelt werden,
wenn er durch eine ärztliche Untersuchung und labortests bestätigt wurde.
Sollten Sie Anzeichen einer allergischen Reaktion wahrnehmen,
so informieren Sie umgehend Ihren Arzt oder Apotheker.
Die gleichzeitige Gabe von Testosteron mit Glukokortikoiden kann die Bildung von Wassereinlagerungen im Gewebe
(Ödeme) fördern. Daher sind diese Wirkstoffe,
insbesondere bei Patienten mit Herz- oder Lebererkrankungen oder bei Patienten, die zu Ödemen neigen, vom
Arzt nur mit Vorsicht einzusetzen.
Darüber hinaus gibt es viele Personen, von denen bekannt ist, dass sie diese Testosteronpräparate wie Nugenix über einen längeren Zeitraum einnehmen, ohne
dass Anzeichen von Nebenwirkungen auftreten. Vor einer medikamentösen Testosteronersatztherapie ist unbedingt die Einstellung eines Hormonstatus durch
einen Facharzt erforderlich. Ein unsachgemäßes Behandeln kann unangenehme bis lebensgefährliche Nebenwirkungen haben. Fruchtbarkeit und Spermienqualität werden durch hohe Hormongaben beim Testosterondoping beeinträchtigt, bei bereits
bestehenden Prostatakarzinomen (Prostatakrebs) wird deren Wachstum beschleunigt.
Außerdem stellt der Körper bei erhöhten Testosterongaben die eigene Testosteronproduktion ein. Der in der Behandlung eingesetzte Wirkstoff entspricht
dem natürlich im Körper vorkommenden Testosteron.
Testosteron-Präparate kommen nicht nur bei vielen Männern in der Andropause zur Verordnung, auch Frauen nehmen spezielle Präparate mit Testosteron ein, wenn bei ihnen eine
solche Hormontherapie angezeigt ist. Bei einer Testosteron-Ersatztherapie kommt es insbesondere auf die Höhe der Dosierung an. Schon kleinste Überdosierungen der hochwirksamen Testosteron-Präparate können gravierende Folgen haben und nicht
bei jeder Behandlung ist die Dosierung verschreibungspflichtiger Haferflocken testosteron Killer-Präparate unproblematisch.
Sehr selten (bei weniger als einem von zehntausend Patienten) entwickelt sich die Nebenwirkung Laktatazidose.
Hierbei kommt es zu einer Übersäuerung des Körpers durch Milchsäure, was bisher größtenteils bei Patienten mit Nierenleiden beobachtet wurde.
Zeichen einer Metformin-Laktatazidose sind Muskelschmerzen, Unwohlsein, Bauchschmerzen, Schnappatmung und eine niedrige Körpertemperatur.
Kiefernpollen sind besonders reich an testosteronähnlichen Pflanzenhormonen.
Testosteronundecanoat a thousand mg Injektionslösung darf nicht in mehrere Portionen aufgeteilt werden. Auch
darf es keinesfalls in den Oberarm oder den Oberschenkel injiziert werden. Die bevorzugte Stelle
für die intramuskuläre Injektion ist der Musculus gluteus medius im oberen äußeren Quadranten der Gesäßregion.
Andernfalls steigt die Gefahr für unerwünschte Nebenwirkungen an (Cushing-Syndrom).
Eine hohe Prednisolon-Dosierung von etwa 1000 Milligramm pro
Tag wird nur zur wenige Tage andauernden Stoßtherapie eingesetzt.
Das Post-Pill-Syndrom beschreibt die Symptome, die nach
dem Absetzen der Antibabypille auftreten können, wenn sich der Körper
wieder an den natürlichen Hormonhaushalt anpasst. Es kann in der Regel ein paar Wochen bis
maximal 6 Monate anhalten, während sich der Körper wieder auf den natürlichen Zyklus einstellt.
Sie haben Beschwerden und Ihr Testosteronwert im Blut ist zu niedrig, übernimmt in der
Regel Ihre Krankenkasse die Kosten der Behandlung. Der Erwerb und Besitz nicht geringer Mengen Dopingmittel wie Testosteron und
Anabolika ist strafbar. Doping ist nicht mehr nur ein Thema unter Spitzen- und Extremsportlern. Längst
ist der Griff zu leistungssteigernden Substanzen auch im Breitensport zu einer erschwinglichen und
häufigen Praxis geworden. In der für Erwachsene in Deutschland
üblichen Dosierung von 250 mg 24 kann Testosteron-Enantat alle 2 bis
3 Wochen injiziert werden. Nehmen ältere Männer das Sexualhormon Testosteron ein, stärkt dies nicht nur die Muskeln, sondern birgt auch Gefahren für Herz und
Kreislauf – bis hin zum Herzinfarkt. Grundsätzlich kann die Pille abgesetzt und später wieder eingenommen werden.
Wenn ein Arzt die Anabolika verschreibt, zur Behandlung von bestimmten Krankheiten, ist der Arzt
sofort zu informieren, wenn Nebenwirkungen von Testosteron auftreten. Testosteron ist
ein Steroidhormon aus der Gruppe der Androgene, das eine zentrale Rolle in der Entwicklung
und Aufrechterhaltung männlicher Geschlechtsmerkmale spielt.
Es wird hauptsächlich in den Hoden bei Männern und in geringeren Mengen in den Eierstöcken bei Frauen sowie in den Nebennierenrinden beider Geschlechter
produziert. Testosteron wirkt durch Bindung an Androgenrezeptoren in Zielzellen, was zur Transkription spezifischer Gene
führt und eine Vielzahl von physiologischen Effekten hervorruft.
Es wirkt durch Bindung an Androgenrezeptoren, wodurch es die Genexpression beeinflusst und die Proteinsynthese fördert.
Die Einnahme von Hormonen kann erhebliche gesundheitliche Nebenwirkungen haben. Aus diesem Grund sprechen erfahrene Bodybuilder
häufig von der “ganz-oder-nie-Entscheidung”.
Die steigende Unzufriedenheit sorgt häufig dazu, dass die “einmalige”
Testosteron-Kur zum Dauerzustand wird.
Durch die Operation sinkt der Testosteronspiegel bei ihnen nämlich innerhalb weniger Tage um
etwa 50 Prozent. Ansonsten wird Frauen von einer Testosteronersatztherapie abgeraten. Gelegentliche Nebenwirkungen (d.h.
Nebenwirkungen bei weniger als einem Prozent der Behandelten) umfassen Schlaflosigkeit, Gewichtszunahme,
Benommenheit, Erbrechen, Bauchschmerzen und Hautausschläge.
Noch seltener sind eine Mangel an Blutplättchen (Thrombozytopenie), Sehprobleme, Hörprobleme und ein angioneurotisches Ödem (spezielle Form von Ödem).
Die Testosteronpräparate (Nebido®, Testogel®, Tostran® usw.) sind zur Testosteron-Ersatztherapie bei männlichem Hypogonadismus indiziert, wenn
der Testosteronmangel klinisch und labormedizinisch bestätigt
wurde. Vor einer notwendigen Testosteron-Behandlung wird
Sie der Hausarzt oder Internist zur Prostatauntersuchung an einen Facharzt überweisen. Als Experten für Testosteronmangel und
dessen Behandlung gelten Urologen beziehungsweise Andrologen.
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